Biotech Hangover from Earnings Clouds Outlook

On October 16 we posted that Risks were Rising for the 2017 biotech rally primarily because technicals were weakening off the top and healthcare politics created a lot of uncertainty. Then we got hit with mixed earnings from several large cap biopharmaceutical companies taking them down 7- 10%  over the past month. The large cap weighted IBB is down about 8% over one month and off its October high of $342.50. Moreover the IBB is approaching its 200 day moving average at $309. We added the IBB  to our portfolio on 6/29/16 at a price of $250.

Our top rated Abbvie (ABBV) was up over 4% for the past month  and 51.3% YTD because of strong earnings with 8.8% revenue growth. Celgene (CELG) showed product line growth of 11% but the stock tanked 25% over the past month primarily because of lower revenue guidance of $19-20B for 2020 compared to previous forecast of $21B with slightly reduced EPS. Celgene has a deep and broad pipeline for cell-based therapies for leukemia, lymphoma and multiple myeloma but has been an overwhelming top pick for many analysts. This could account for the big price drop.

During the same rocky 30 day period high profile mid-caps were also weak but Alnylam (ALNY) was a winner up over 7% (until today hit by a public offering), but Incyte (INCY) was a loser down 6%. Keep the longer term trend in perspective because although the small cap weighted XBI is down over 6% for the month it is still up 37% YTD. Nektar Therapeutics (NKTR) soared 14% yesterday on upbeat data from their therapeutic cancer treatment NK-214 in a combination trial with Opdivo (Bristol-Myers Squibb) across several tumor types.